Federated Transfer Learning Models for Privacy-Preserving Predictive Diagnostics in Heterogeneous Healthcare Systems Using Distributed Cloud Computing Frameworks
Keywords:
Federated learning, transfer learning, privacy preservation, healthcare diagnostics, cloud computing, model generalization, heterogeneous systemsAbstract
The growing need for predictive diagnostics in healthcare demands both high-performing models and strict privacy assurances. This study presents a federated transfer learning (FTL) approach deployed within a distributed cloud computing framework to facilitate diagnostic predictions without centralized data collection. Addressing the heterogeneity of healthcare data across institutions, our method ensures privacy-preserving collaboration while enhancing model generalizability. We evaluate this approach on synthetic and real-world datasets (MIMIC-III and COVIDx), demonstrating its efficacy in maintaining diagnostic accuracy and minimizing data exposure.
References
Li, Tian, Anit Kumar Sahu, Manzil Zaheer, Maziar Sanjabi, Ameet Talwalkar, and Virginia Smith. "Federated Optimization in Heterogeneous Networks." Proceedings of Machine Learning Research, vol. 100, 2020, pp. 429–450.
Subramanyam, S.V. (2025). Cloud-based enterprise systems: Bridging scalability and security in healthcare and finance. International Journal on Science and Technology (IJSAT), 16(1), 1–20.
Sheller, Micah J., G. Anthony Reina, Brandon Edwards, Jason Martin, and Spyridon Bakas. "Multi-Institutional Deep Learning Modeling Without Sharing Patient Data: A Feasibility Study on Brain Tumor Segmentation." BrainLes 2018, Springer, 2020, pp. 92– 104.
Zhang, Kai, Xin Song, Yujin Huang, Hui Wu, and Yuan Li. "Cross-Domain Transfer Learning for COVID-19 Diagnosis Using Chest X-Ray Images." Computers in Biology and Medicine, vol. 132, 2021, p. 104306.
Subramanyam, S.V. (2025). Revolutionizing enterprise workflows: The role of declarative rules in business process systems. International Journal of Information Technology and Management Information Systems (IJITMIS), 16(2), 341–365.
Xu, Jing, Zhen Wang, Shuang Liu, and Kun Lin. "Federated Transfer Learning for Personalized Heart Disease Prediction." IEEE Journal of Biomedical and Health Informatics, vol. 26, no. 4, 2022, pp. 1668–1679.
Al-Rakhami, Mona, and Mohammed Al-Qurishi. "Privacy-Preserving Machine Learning in Federated Healthcare Environments: Opportunities and Challenges." ACM Computing Surveys, vol. 55, no. 2, 2023, pp. 1–39.
Subramanyam, S.V. (2021). Cloud computing and business process re-engineering in financial systems: The future of digital transformation. International Journal of Information Technology and Management Information Systems (IJITMIS), 12(1), 126–143.
Yang, Qiang, Yang Liu, Tianjian Chen, and Yongxin Tong. "Federated Machine Learning: Concept and Applications." ACM Transactions on Intelligent Systems and Technology (TIST), vol. 10, no. 2, 2019, pp. 1–19.
Rieke, Nicola, Jake Hancox, Wenqi Li, Fausto Milletari, Holger R. Roth, Saeed Albarqouni, and M. Jorge Cardoso. "The Future of Digital Health with Federated Learning." NPJ Digital Medicine, vol. 3, no. 1, 2020, pp. 1–7.
Subramanyam, S.V. (2023). The intersection of cloud, AI, and IoT: A pre-2021 framework for healthcare business process transformation. International Journal of Cloud Computing (IJCC), 1(1), 53–69.
Kairouz, Peter, H. Brendan McMahan, Brendan Avent, Aurélien Bellet, Mehdi Bennis, Ahmad Al-Nasr, and Sen Zhao. "Advances and Open Problems in Federated Learning." Foundations and Trends in Machine Learning, vol. 14, no. 1–2, 2021, pp. 1–210.
He, Zhen, Xingxing Zhang, Linxing Xing, and Xiaoxiang Xie. "Personalized Federated Learning for Intelligent Health Diagnosis." IEEE Internet of Things Journal, vol. 8, no. 8, 2021, pp. 4476–4486.
Subramanyam, S.V. (2024). Transforming financial systems through robotic process automation and AI: The future of smart finance. International Journal of Artificial Intelligence Research and Development (IJAIRD), 2(1), 203–223.
Kaissis, Georgios A., Markus R. Makowski, Daniel Rückert, and Rickmer F. Braren. "Secure, Privacy-Preserving and Federated Machine Learning in Medical Imaging." Nature Machine Intelligence, vol. 2, no. 6, 2020, pp. 305–311.
Tan, Chuanqi, Fuchun Sun, Tao Kong, Wenchang Zhang, Chao Yang, and Chunfang Liu. "A Survey on Deep Transfer Learning." Proceedings of the 27th International Joint Conference on Artificial Intelligence (IJCAI), 2018, pp. 2704–2710.
Rajkomar, Alvin, Jeff Dean, and Isaac Kohane. "Machine Learning in Medicine." New England Journal of Medicine, vol. 380, no. 14, 2019, pp. 1347–1358.
Kumar, K. (2020). Enhancing interpretability and explainability in deep neural networks for artificial intelligence. QIT Press - International Journal of Artificial Intelligence (QITP-IJAI), 1(1), 1-4.
Priyadarsini, A. (2024). Advancing the understanding of representation learning in artificial intelligence systems. QIT Press - International Journal of Artificial Intelligence (QITP-IJAI), 5(2), 1-5.
Bansal, A. (2020). Predictive modeling and complex system analysis reimagined through deep learning-powered artificial intelligence. QIT Press - International Journal of Artificial Intelligence and Deep Learning Research and Development, 1(1), 1-4.
Navya, M. (2024). Deep learning as the foundation for advanced cognitive automation and human-machine collaboration in artificial intelligence. QIT Press - International Journal of Artificial Intelligence and Deep Learning Research and Development, 5(2), 1-4.
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